The Leptin/OB Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The Leptin/OB Antibody has been validated for the following applications: ELISA, Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Human leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarilyin the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated,resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes andinfertility. The function of leptin in regulating appetite and metabolism, as well as the possibility of usingleptin as a therapeutic agent, are currently under intense investigation